Anxiety and depression in south east patients with chronic liver disease

Abstract

Background: chronic liver disease patients are more likely to develop anxiety and depression. Objectives: to determine the frequency and disease specifics factors associated with depression and anxiety in patients with chronic liver disease. Methods: This is an cross-sectional study conducted at aims hospital, Hyderabad, Pakistan After approval from the Institutional Review Board (IRB) dated 20/12/20, IRB No. 0137 with the age group of 18 to 60 years old adults attended gastroenterology clinic from the period of January to June 2021.assessment of mental status of the patients by using Depression Anxiety Stress Scale-21 (DASS-21).this scoring system has 21 questions with each part having further seven questions and on the basis of these question we measures the grading of anxiety and depression .the score is ranges from 0-21 score. Patients with score upto 7 shows normal level of depression ,8-9 mild level of depression ,10-13 moderate level of depression ,14- 15 severe depression and score of 25 shows extreme level of depression. Results: 16.5% of them had moderate depression. There are statistically significant differences between gender, patient education, ascites, child pough classification, comorbid diabetes and mean depression, anxiety and stress scores. Comorbid diabetes and decompensated cirrhosis significantly increase risk of depression by 3.84 and 17.7 folds respectively. Conclusion: pychaitry symptoms are more common in males , highly educated patients, in diabetes and in advanced liver disease patients