Serology as precise diagnostic tool in covid-19

Abstract

Since its origin in Wuhan, China in the last week of December 2019, the coronavirus infectious disease-2019 (COVID-19), caused by the β-Coronavirus, dubbed SARS-CoV-2 has been a global pandemic affecting 212 countries and territories worldwide spanning all five continents. For its management and eradication, prompt and accurate diagnosis of the disease is central. For the diagnosis of SARS-CoV-2 in respiratory clinical specimens, real-time polymerase chain reaction (realtime PCR) using dual labelled TaqMan probe and targeting two genomic areas, typically RdRp and envelope (E) regions, of the virus is commonly used.