ASSOCIATION OF VITAMIN D STATUS WITH GLYCEMIC CONTROL IN TYPE II DIABETIC PATIENTS

Abstract

Objective: To determine the association of vitamin D levels with glycemic control in type II diabetic patients. Study setting: Physiology department and diabetic clinic, LUMHS Jamshoro from March 2020 to August 2020
Methods: This study comprised all male and female type II diabetic patients (n=196), of age group ≥18 years. After taking all aseptic measures, 10cc blood taken intravenously in study population. Serum vitamin D3 levels determined by using 3L52 ARCHITECT 25 –OH Vitamin - D Reagent kit. Hemoglobin A1c determined on Cobas e411 Roche. Data entered in predesigned proforma and then to SPSS data sheet and analyzed on IBM, SPSS VERSION 22.0.
Results: Mean±SD of age (in years), vitamin D levels(ng/ml) and hemoglobin a1c in study population (n=196) were43.57±9.59, 24.6±12.7 and 8.27±2.15 respectively. Deficient vitamin D levels found in 47.8 percent type II diabetic group having hemoglobin a1 c >8.0gm%, (P-value<0.01, Pearson chi square value=27.74, df=4). Vitamin D levels were negatively related to glycemic control in diabetic type II patients, r- value=-0.18 and p value <0.01.
Conclusion: Deficient vitamin D levels are related with poor glycemic control in type II diabetes mellitus.
Keywords: Vitamin D, Hemoglobin a1c, diabetes type II